Sibutramine is an orally administered agent for obesity treatment, weight loss and weight maintenance in adults aged 16 years and above. Sibutramine, otherwise a relatively new compound, is known to promote and maintain reduced weight in obese patients for up to 2 years. This appetite suppressing obesity treatment is particularly approved for use in people with a BMI of 30 or greater or a BMI of 27 or greater in conjunction with definite risk factors such as high cholesterol or diabetes.
Sibutramine's mechanism of action includes affecting certain brain chemicals that cause a feeling of satiety. Sibutramine is readily available under the brand name Reductil, a prescription weight-loss obesity treatment, and promotes quick weight reduction. In fact, Reductil (Sibutramine), with its strong appetite suppressing action, when used in combination with a low-calorie diet allows for consumption of fewer calories.
As known to all of us, obesity is constantly on the rise and as a result the search for a workable obesity treatment has intensified. The perfect weight loss plans involve a gradual decrease in weight and this is achieved by consuming a healthy diet and increasing the level of one’s physical activity. Although, most of the weight loss plans and obesity treatment plans are difficult to follow as a routine, positive lifestyle changes do go a long way in making weight reduction a more achievable goal when undergoing obesity treatment. It is believed that some 8.5 million individuals in more than 70 countries have successfully used Reductil Sibutramine to promote effective weight reduction.
Although bariatric surgery is very much a weight reducing aid, it is still considered an exceptionally drastic measure, and is seldom considered for obesity treatment unless all other options have been exhausted. Therefore most people, when going for obesity treatment, consider using Reductil Sibutramine weight-reduction pills, and more so if there is a past history of failed attempts at successfully controlling their obesity. While there are many non-prescription and over-the-counter drugs on the market that might be suspect, Sibutramine, an approved obesity treatment, has been shown too safely and effectively control obesity.
During obesity treatment, Sibutramine as an appetite suppressant acts in the brain where it increases the levels of certain brain chemicals like serotonin, norepinephrine, and dopamine through its mechanism of action in specific areas of the brain. Sibutramine, the active ingredient in Reductil, in no way increases the production of brain chemicals. But alternatively Sibutramine works to prevent the "reuptake" of noradrenaline and serotonin in the central nervous system. In addition, Sibutramine augments satiety signals and potentiates energy spending by stimulating thermogenesis.
What really happens when you take Sibutramine though, how does this obesity treatment really work? Basically, as soon as a message travels from the nerves to the cells, Sibutramine causes the end of the cell to release a brain chemical. This chemical then enters the gap between the first nerve cell and the one next to it. When the required amount of chemical reaches the second nerve cell, Sibutramine works to activate the receptors on the cell, and the message continues on its way. The first cell then quickly absorbs any of the extra chemical that remains in the gap between the cells, preventing the chemical from further activating the second cell. This is called "reuptake." As a result of Sibutramine blocking the reuptake of chemicals, promotes a sense of fullness.
Reductil is thus effective in patients with diabetes, hypertension and dyslipidaemia, as well as ethnic sub-populations, in whom obesity may otherwise pose a particular problem of increased comorbidities. Reductil can therefore be considered an safe and effective method of obesity treatment.